Psychedelics Content / Psychedelics Content for Â鶹´«Ă˝ en Â鶹´«Ă˝ Researchers Achieve Total Synthesis of Ibogaine /health/news/uc-davis-researchers-achieve-total-synthesis-ibogaine <p><span>Ibogaine — a psychoactive plant derivative — has attracted attention for its anti-addictive and anti-depressant properties. But ibogaine is a finite resource, extracted from plants native to Africa like the iboga shrub (</span><em><span>Tabernanthe iboga</span></em><span>) and the small-fruited voacanga tree (</span><em><span>Voacanga africana</span></em><span>). Further, its use can lead to irregular heartbeats, introducing safety risks and an overall need to better understand how its molecular structure leads to its biological effects.&nbsp;</span></p> February 06, 2025 - 10:45am Andy Fell /health/news/uc-davis-researchers-achieve-total-synthesis-ibogaine Anti-Anxiety and Hallucination-Like Effects of Psychedelics Mediated by Distinct Neural Circuits /news/anti-anxiety-and-hallucination-effects-psychedelics-mediated-distinct-neural-circuits <p><span>New research suggests that it could be possible to separate treatment from hallucinations when developing new drugs based on psychedelics. The anti-anxiety andhallucination-inducing qualities of psychedelic drugs work through different neural circuits, according to research using a mouse model. </span><a href="https://doi.org/10.1126/science.adl0666"><span>The work is published Nov. 15 in Science</span></a><span>.&nbsp;</span></p> November 14, 2024 - 10:06am Andy Fell /news/anti-anxiety-and-hallucination-effects-psychedelics-mediated-distinct-neural-circuits Exploring the Psychedelics Within Us /blog/exploring-psychedelics-within-us <p><span>Our bodies are pharmaceutical factories. From the hormones that regulate our blood sugar to the neurotransmitters that act as the body’s natural painkillers, these endogenous — produced within the body — chemicals ensure our functionality and survival.</span></p><p><span>But did you know that our bodies also naturally produce psychedelics?</span></p><p><span>In the 1950s, researchers found chemical signatures of N,N-dimethyltryptamine (DMT) in mammalian bodies, including in humans.</span></p> October 21, 2024 - 3:00pm Andy Fell /blog/exploring-psychedelics-within-us New Method Tracks How Psychedelics Affect Neurons in Minutes /news/new-method-tracks-how-psychedelics-affect-neurons-minutes <p><span>Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs. The protein-based tool, which is called Ca<sup>2+-</sup>activated Split-TurboID, or CaST, is described in research published in </span><a href="https://www.nature.com/articles/s41592-024-02375-7"><span>Nature Methods</span></a><span>.&nbsp;</span></p> August 05, 2024 - 10:22am Andy Fell /news/new-method-tracks-how-psychedelics-affect-neurons-minutes Receptor Location Matters for Psychedelic Drug Effects /health/news/receptor-location-matters-psychedelic-drug-effects A new study reveals receptor location impacts psychedelic drug effects. Learn how Â鶹´«Ă˝ researchers are exploring implications for mental health treatment. February 16, 2023 - 11:00am Andy Fell /health/news/receptor-location-matters-psychedelic-drug-effects Â鶹´«Ă˝ Establishes Institute for Psychedelics and Neurotherapeutics /health/news/uc-davis-establishes-institute-psychedelics-and-neurotherapeutics <p><span><span><span><span><span><span><span><span>The University of California, Davis, has launched the <a href="https://neurotherapeutics.ucdavis.edu/"><strong>Institute for Psychedelics and Neurotherapeutics</strong></a> to advance basic knowledge about the mechanisms of psychedelics and translate it into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer’s disease and Parkinson’s disease, among others.</span></span></span></span></span></span></span></span></p> February 02, 2023 - 5:00am Andy Fell /health/news/uc-davis-establishes-institute-psychedelics-and-neurotherapeutics PsychLight Sensor to Enable Discovery of New Psychiatric Drugs /news/psychlight-sensor-enable-discovery-new-psychiatric-drugs Introducing psychLight: a sensor for mental illness treatment and drug abuse detection. Learn how Â鶹´«Ă˝ researchers are advancing mental health technology. April 28, 2021 - 8:30am Andy Fell /news/psychlight-sensor-enable-discovery-new-psychiatric-drugs New Compound Related to Psychedelic Ibogaine Could Treat Addiction, Depression /news/new-compound-related-psychedelic-ibogaine-could-treat-addiction-depression <p>A non-hallucinogenic version of the psychedelic drug ibogaine, with potential for treating addiction, depression and other psychiatric disorders, has been developed by researchers at the University of California, Davis. A paper describing the work is published Dec. 9 in Nature.</p> <p>“Psychedelics are some of the most powerful drugs we know of that affect the brain,” said David Olson, assistant professor of chemistry at Â鶹´«Ă˝ and senior author on the paper. “It’s unbelievable how little we know about them.”</p> December 09, 2020 - 8:08am Andy Fell /news/new-compound-related-psychedelic-ibogaine-could-treat-addiction-depression Psychedelic Drugs Change Structure of Neurons /news/psychedelic-drugs-change-structure-neurons <p>A team of scientists at the University of California, Davis, is exploring how hallucinogenic drugs impact the structure and function of neurons — research that could lead to new treatments for depression, anxiety&nbsp;and related disorders.</p> June 12, 2018 - 6:58am Andy Fell /news/psychedelic-drugs-change-structure-neurons